Jogging along Sunset Canyon Drive in Burbank is great. You have the choice of peeling off into several great mountain trails, or you can just keep running the border line between the rugged Verdugo Mountains and the city of Burbank. From Sunset Canyon drive you are high enough to see the entire San Fernando Valley, as well as a glimpse of the Los Angeles skyline off to the south.
The best time is during sunset, as you see the tall Mexican Fan Palms dancing along the top of the city like a hundred green cotton balls and tumble weeds being whacked around the sky by tall Italian Cypress trees. The sunset brings out exciting colors of the palms, the city, and the rich reds, oranges, and the greens of the Verdugo Mountains. And the softness of the sun brings a warm softness to the community - a period of calm in a sea of dense humanity.
On those occasions when you really want a good workout, and have a burning desire to run the mountains, heading up Harvard Road to the Wildwood Canyon Road is a great place to unload excess energy. In addition, you will take the wonderful views you get on Sunset Canyon, and multiply them 10 fold. However you need to have a real feel for off road running, as the trails soon get steep, and are not that hospitable for the casual runner.